- Foreword
- Dedication
- Glossary of Terms
- Chapter 1: Inflammation and The Inflammatory Response
- Chapter 2: Effects of the Inflammatory Response
- Chapter 3: Effects of the Inflammatory Mediators
- Chapter 4: The Complex interaction of Inflammatory Mediators
- Chapter 5: Natural Suppression of the Inflammatory Response
- Chapter 6: Inflammatory Pain Syndromes
- Chapter 7: Current Treatment for Persistent Pain
- Chapter 8: Reasons why Current Treatment May Not Relieve Persistent Pain
- Chapter 9: New Breakthrough Treatment Options for Persistent Pain
- Chapter 10: L.A. Pain Clinic CASE REPORTS
- Conclusion
- About the Author
- About the Book
- References
Sota Omoigui MD |
|
This is a numbing disorder of the hand that rarely affects men but is fairly common in women. The carpal tunnel is a passageway that leads through your wrist. The area is called a tunnel because it has bones on three sides and a ligament on the palm side. Feel your wrist. Can you feel that it has three bony sides and soft tendons on the underside? The carpal tunnel protects the median nerve that runs inside and provides sensation to your fingers. Normally you aren't conscious of that nerve, but when tissues in the tunnel swell from inflammation, there's less room in the area and the median nerve becomes irritated and inflamed. People with carpal tunnel syndrome (CTS) experience numbness, tingling and pain in the fingers, wrist and even the arm. It is commonly described as pins and needles tingling or fingers going to sleep, such as when you've rested on a part of your body for a long time. The pain is worse at night when your body is warm and blood vessels expand taking up more space in the carpal tunnel. CTS may be brought about by activities that involve repeated or strenuous use of the wrists. Repetitive motions may range from typing all day at a computer to biking or playing tennis on a regular basis. Staying in one position for so long that it causes compression on the nerve such as during a long bike ride may also cause CTS. Swelling and pressure and carpal tunnel syndrome may also be caused by conditions such as arthritis, diabetes, low levels of thyroid hormones, pregnancy, hormonal changes associated with menopause and broken or dislocated bones in the wrist. When sitting at a keyboard, make sure your hands are at elbow level or slightly below elbow level to prevent excess bending or stretching in the wrist. You may also use a wrist rest that is a foam pad placed at the end of the keyboard for extra support. Take a break every hour or two or whenever you feel tired, to change your posture. Lean back and take your hands off the keys. Take a second to bend your wrists the opposite way from the position they normally maintain. Stretch your fingers and shoulders, moving them around naturally to get them out of the fixed position. Take a thick rubber band and place it around the tips of your fingers including your thumb. Now open and close your fingers. For more wrist exercises, you may squeeze a tennis ball several times a day or try sports dough called "Power Putty" If you ride bikes; you should wear properly padded biking gloves and change positions during a long ride. If you play tennis or handball, take lessons to learn the proper grip. If you are pregnant, the numbness will disappear after the baby is born. Treating any of the conditions mentioned above (arthritis, diabetes, low levels of thyroid hormones, hormonal changes associated with menopause, broken or dislocated bones in the wrist) should also bring relief to your CTS. Aspirin or other over the counter pain relievers such as Aleve, Motrin or Tylenol may relieve the pain. Take herbal supplements such as Quercetin, Rutin, Curcumin, Red Wine tablets, Cinnamon and Ground Clove Extracts. These contain polyphenols which are the best anti-inflammatory agents that nature has provided to us. Your doctor should first prescribe a wrist splint to help hold the wrist in an upward position. This position is important because it allows the nerve the room it needs. The splint may be worn round the clock or only at night depending on what gives you the most comfort. Elevate your hands when you sleep so that fluid drains back down your arm and decompresses the tunnel through which the nerve is passing. Strap an ice pack to your wrist for 10 20 minutes; place your wrists under a cold running tap or soak in an ice water bath to relieve the inflammation. You may add a few tablespoons of salt to the water bath. A therapist may do paraffin or hot wax bath and wrist massage. If you are not feeling better after a few weeks, your doctor may recommend a cortisone injection in the wrist. The purpose of the cortisone is to decrease inflammation and thus decrease the swelling around the tendons. It is like putting the aspirin right into the wrist. Some people get better after one injection. Others might require a repeat. Cortisone should not be used frequently because it may cause the tendons to breakdown. Cortisone may also be injected in the muscle or in an intravenous (IV) line. Other drugs that help control the median nerve inflammation include a subcutaneous injection of the biologic drug Kineret as well as an intravenous (IV) infusion of the anti-seizure drug Depacon combined with IV infusion of magnesium sulfate. Vitamin B2 (riboflavin) and Vitamin B6 (pyridoxine) supplements may be helpful especially if you have a deficiency of the vitamin. However excess doses of Vitamin B6 may also cause nerve damage. If these treatments do not work, then surgery may be necessary. The procedure called a "release" involves cutting the ligament forming the roof of the carpal tunnel to relieve pressure on the median nerve. The operation is usually done on an outpatient basis and successful in most cases. Before you consider surgery, make sure you've made changes in the work place and seen a physical or occupational therapist to learn new ways to work or play. Surgery may not be able to undo muscle or nerve problems brought on by years of strain. Even after surgery, these changes will still be necessary if you do not want your CTS symptoms to come back. |
Call your Doctor : If making changes in the way you work or play doesn't seem to help and the pain is sufficient to keep you awake at night.
|
- Pharmacokinetic–pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors
- Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats
- Multimodal pain management in veterinary medicine: the physiologic basis of pharmacologic therapies
- Antiinflammatory and antihyperalgesic activity of C-phycocyanin
- Synthèse des mécanismes impliqués dans un syndrome douloureux complexe: la fibromyalgie
- Use of indazole derivatives for the treatment of neuropathic pain
- Treatment of chronic bilateral knee pain without objective clinical findings: Central sensitization. A case report
- Role of the sympathetic nervous system in chronic post ischemia pain, a rodent model of complex regional pain syndrome type
- Pharmacological profile of three different ?-butyrolactone derivatives in mice
- Comparison of the effects of tramadol, codeine, and ketoprofen alone or in combination on postoperative pain and on concentrations of blood glucose, serum cortisol, …
- INTERAÇÃO ENTRE FATORES AMBIENTAIS EA VARIAÇÃO NO GENE DA APOLIPOPROTEÍNA E (APOE) NA DETERMINAÇÃO DA SUSCETIBILIDADE À …
- VULVODINIA: UN DIAGNÓSTICO OLVIDADO FRENTE AL DOLOR VULVAR
- ????? ????????? ???????????? ???? ? ??????? ??????????????? ??????????? ????? ? ?????
- Caratterizzazione farmacologica di nuovi composti oppioidi per la terapia del dolore
- physique et douleur
- Cyclosporine A in the treatment of Interstitial Cystitis
- ????????????????????
- Recherche sur les effets de l'analgésie périopératoire optimale (RAPO) sur la douleur et la fonction après chirurgie de la main
- Mediadores inflamatórios na dor pélvica crônica-Identificação de possíveis marcadores séricos da doença
Fibromyalgia
Sports Medicine
General Rheumatology
- General
- Arthritis
- Back Pain
- Cancer Pain
- Carpal Tunnel Syndrome
- Diabetes Pain
- HIV/AIDS Pain
- Interstitial Cystitis
- Fibromyalgia Pain
- Labor Pain
- Menstrual Pain
- Migraine Headache
- Reflex Sympathetic Dystrophy
- Sickle Cell Disease
- Shingles/Post-herpetic Neuralgia
- Tension Headache
- Trigeminal Neuralgia
- Vulvodynia
Medical Publications
- The biochemical origin of pain: The origin of all pain is inflammation and the inflammatory response. Part 2 of 3 – Inflammatory profile of pain syndromes
Omoigui S. - The Interleukin-6 inflammation pathway
from cholesterol to aging - Role of statins, bisphosphonates and plant
polyphenols in aging and age-related diseases.
Omoigui S. - The biochemical origin of pain - Proposing a new law of pain: The origin of all pain is inflammation and the inflammatory response. Part 1 of 3 - A unifying law of pain.
Omoigui S. - Bevel Design and not Needle Length determines the Pain Experience in Patients receiving Injections
Omoigui S., Adewumi PA, Do Y, Elenes G. - Cholesterol Synthesis is the Trigger
Omoigui S. MD. - Treatment of ptosis as a complication of botulinum toxin injection
Omoigui S, Irene S. - Subcutaneous Injection of Anakinra
Omoigui S. MD. - A Safer Technique for Epidural Lysis of Adhesions
Omoigui S. MD. - Blind nasal intubation with Audio-Capnometry
Omoigui S, Glass P, Martel DL, Watkins K, Williams KL, Whitefield SM, Wooten LL.
Rheumatology Headlines
Anesthesiology
Pain Management
Android, iPhone, iPod touch, BlackBerry, Palm, Palm Pre, Windows Mobile and Nokia Symbian
BREAKING NEWS!!!!!!:
Page 18 in ARTICLE from Department of Pharmacology, Leiden /Amsterdam Center for Drug Research (LACDR), Faculty of Science, Leiden University STATES:
“we strongly support the hypothesis proposed by OmoiGui, which states that the origin of all pain is inflammation and inflammatory response (5;6).”
Click here to read:
Beyond relief : biomarkers of the anti-inflammatory effect and dose selecion of COX inhibitors in early drug development. Huntjens, Dymphy Regien Hans
Click here to download Full text article from Center for Drug Research:
Click here to read the latest Journal Articles citing Sota Omoigui’s Law of Pain:
BREAKING NEWS!!!!!!:
NOW PUBLISHED – PROCEEDINGS OF THE L.A. PAIN CLINIC
Click here to read the current case report or research article:
Medicinehouse.com Jan 2009; [Epub ahead of print]
Click here to download PDF article:
A critical review of the evidence - Spinal Pain and Fluoroscopic Guided Facet Joint Nerve and Epidural Injection; Full Text Article
BREAKING NEWS!!!!!!:
JUST PUBLISHED - Part 2 of Sota Omoigui’s Law of Pain describing the Inflammatory Profile of Pain Syndromes
Listed on Science Direct Top 25 Hottest Articles
Click here to read:
Med Hypotheses. 2007 Aug 27; [Epub ahead of print]
Click here to download article:
Med Hypotheses. 2007 Aug 27; Full Text Article
NOW AVAILABLE
!!!!!!:
The Biochemical Origin of Pain
Containing Part 1, Part 2 and Unpublished Part 3 of Sota Omoigui’s Law of Pain
Click here to Order Book:
BREAKING NEWS!!!!!!:
JUST PUBLISHED IN THE UK – HOSPITAL DOCTOR profiles Sota Omoigui’s Law of Pain and asks “Is it time for RETHINKING PAIN?”
Click here to read and download:
RETHINKING PAIN
Hospital Doctor 2007 June Pg 24
BREAKING NEWS!!!!!!:
JUST PUBLISHED – Dr Sota Omoigui contributes a chapter in the Textbook – IMMUNE DYSFUNCTION AND IMMUNOTHERAPY IN HEART DISEASE - Edited by: Ronald Ross Watson (Professor of Public Health, School of Medicine, University of Arizona, Tuscon, ) and Douglas Larson.
Click here to view the cover:
Immune Dysfunction and Immunotherapy in Heart Disease
BREAKING NEWS!!!!!!:
In the Journal of Immunity and Ageing, Dr Sota Omoigui describes the Inflammation Pathway from Cholesterol to Aging.
Listed on Immunity and Ageing
Top 10 Most Accessed Articles of All Time
Click here to read:
Immun Ageing. 2007 Mar 20;4(1):1 [Epub ahead of print]
Medical Publications
U.S. Patents
Search prescription drugs on Drugs.com






































Our advanced pain therapies have been successful in patients with the most refractory
pain syndromes including Nerve Inflammation, Herniated and Degenerative Disks
before and after surgery, Sciatica, Spinal Cord Inflammation, Reflex Sympathetic Dystrophy
(RSD/CRPS), Arthritis, Osteoarthritis, Osteoporosis, Tendonitis, Bursitis, Fibromyalgia,
Neuropathic Pain Syndromes, Neurogenic Inflammation, Vulvodynia, Migraine,
Chronic Daily Headache, Cluster headache, tissue inflammation from Drug Extravasations etc. 
ABOUT THE BOOK
Designed for quick access to essential anesthesia drug information, The Handbook is a complete clinical guide in a handy portable format. This pocket reference is packed with tables, descriptions and expanded dosing information covering a broad range of drugs and the various routes of administration commonly used in the practice of anesthesia and critical care. As a synopsis of anesthetic pharmacology it is a useful review for the beginning trainee and the advanced practitioner. An all-time best seller, The Anesthesia Drugs Handbook has been translated into Italian, Japanese, Malaysian, Polish and Portuguese.
Designed for quick access to pain drugs information, Sota Omoigui's Pain Drugs Handbook is a complete clinical guide in a handy portable format. This pocket reference is packed with tables, descriptions and dosages covering a broad range of drugs and the various routes of administration commonly used in the treatment of acute, chronic and cancer pain.
This booklet is written to guide those who suffer or know someone suffering from pain. It provides the most current information about the common painful syndromes, the right medications, useful herbs and various treatments that can be utilized in the home, clinic or hospital to successfully ease pain.
Medications and Plants that prevent and treat Aging, Cardiovascular Disease, Osteoporosis,Arthritis, Type-2 Diabetes, Dementia and Alzheimer’s Disease.
One of the best books on Self Improvement and Management ever published. Animals have been taking care of business much longer than humans and they do it with an instinct few humans possess. Yes, we can learn a lot from the animal kingdom and everyone should read this book. Having been an avid animal behavior student for many years the author has observed their lessons and been awed by them.








