- Foreword
- Dedication
- Glossary of Terms
- Chapter 1: Inflammation and The Inflammatory Response
- Chapter 2: Effects of the Inflammatory Response
- Chapter 3: Effects of the Inflammatory Mediators
- Chapter 4: The Complex interaction of Inflammatory Mediators
- Chapter 5: Natural Suppression of the Inflammatory Response
- Chapter 6: Inflammatory Pain Syndromes
- Chapter 7: Current Treatment for Persistent Pain
- Chapter 8: Reasons why Current Treatment May Not Relieve Persistent Pain
- Chapter 9: New Breakthrough Treatment Options for Persistent Pain
- Chapter 10: L.A. Pain Clinic CASE REPORTS
- Conclusion
- About the Author
- About the Book
- References
Sota Omoigui MD |
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The symptoms are intense throbbing pain often on one side of the head, which may spread to the entire head, neck and shoulders. Sometimes bright spots, flashing lights or zigzag patterns may be seen prior to the headache. The headache is often present on awakening and may be accompanied by nausea, vomiting, dizziness and tingling in the lips. Bright lights and noises become unbearable. The headache is due to swelling of the blood vessels that go to the scalp and brain. Before swelling, the blood vessels first tighten up, decreasing the amount of blood going to the brain. This produces the visual disturbances and in severe attacks may cause paralysis, and loss of ability to speak. During attacks, some people become pale, with bloodshot eyes and runny nose. Migraine headaches occur most often when unwinding from stress such as during weekends or holidays. In some women, migraine headaches coincide with their menstrual cycle. Get enough rest and minimize stress. Avoid irregular eating habits (which may decrease your blood sugar), certain medications e.g. birth control pills, nitrates. About 20% of migraine sufferers have a sensitivity to certain beverages and foods. Beverages which can trigger an attack include red wine, beer, whiskeys, scotch, tanin containing beverages e.g. apple juice and caffeinated drinks such as coffee, tea and colas, chocolate or cocoa. Foods which can trigger an attack include dairy products such as milk, buttermilk, cream, sour cream, yogurt, hard/aged cheeses, cheddar, brie, processed cheeses, fats and lard. Meats/poultry triggers include processed meats containing sodium nitrite (e.g. hot dogs, bologna), aged, cured smoked, marinated meats, organ meats (e.g. chicken livers). Fish triggers include smoked or dried fish, pickled herring. Vegetable triggers include broad beans, most peas, onions, pickles, olives, sauerkraut. Grains/breads that may precipitate an attack include yeast breads, white breads and sourdough. Soup triggers include any soup containing the additives MSG or yeast and soups from bouillon cubes. Fruit triggers include citrus fruits, other fruits e.g. bananas, figs, raisons, papaya, kiwi, plums, pineapples, avocados. Deserts triggers include chocolates, ice cream, cookies/cakes made with yeast, potato chip products, nuts. Additives such as MSG and other flavor enhancers, artificial sweeteners, seasonings and spices may sometimes be dietary triggers. Start a headache diary for everything you eat or drink and all the medications you take. By checking the diary later you may be able to find out which foods or medicines are bringing on the attacks. If you have menstrual migraine, you may obtain relief by wearing a low dosage (one-fifth of the birth control dosage) estrogen patch on your buttocks. This is worn for three to nine days or during the time you normally get the migraine attack. The estrogen patch evens out the hormonal level, which usually drops just before your cycle starts. If you have more than two migraine attacks a month, you may need to take migraine prevention medications. Anti-seizure medications such as Topamax or Trileptal, antidepressants such as Elavil or Lexapro, beta-blockers such as Propranolol (Inderal), calcium-channel blockers such as Amlodipine (Norvasc), and the anti-inflammatory/muscle relaxant Zanaflex (Tizanidine) help to prevent migraine attacks when taken regularly. It is important to check if you have high blood pressure and treat it as high blood pressure may contribute to headaches. Inderal and Norvasc can both treat high blood pressure as well as prevent migraine. Also check or re-check your eyesight as eye strain may contribute to headaches. Riboflavin (Vitamin B2) has been shown to prevent migraines when taken regularly. Take 200 mg twice daily. This may also be combined with Valerian root to get restful nights sleep (1000 mg at bedtime). Another herbal medication that may help prevent and treat migraine headache is feverfew. Take one to three capsules daily. It takes a few weeks to notice the effects. Feverfew is available at your local health food store. The label should state that it contains 0.2% parthenolide - the active ingredient. Apply a cold cloth or ice pack to your head, or splash your face with cold water. Take herbal supplements such as Quercetin, Rutin, Curcumin, Red Wine tablets, Cinnamon and Ground Clove Extracts. These contain polyphenols which are the best anti-inflammatory agents that nature has provided to us. Take over the counter pain relievers such as Excedrin. Relax if possible. Lie down in a quiet, dark room for several hours. Listen to soft music, sleep or meditate. Your doctor may prescribe migraine triptan medications such as Sumatriptan (Imitrex), Zomig, Frova or Axert tablets. Sumatriptan is available as an injection and your doctor can teach you how to give yourself the injection. Sumavel is an injection of Sumatriptan that uses compressed air and does not have a needle. It is easier to use than the regular Imitrex patient injection kits. Imitrex and Zomig are also available as a nasal spray. Carry your medications with you at all times. Migraine medications used to abort an attack are more effective if taken at the onset. Older migraine medications such as Ergotamine or Midrin are not as effective and may be associated with more side effects such as nausea, vomiting, chest pain, increasing headache or cold extremities. Ergotamine tablets can be taken by mouth or sublingually which means you place the tablet under your tongue. D.H.E. (Dihydroergotamine) is a derivative of ergotamine with fewer side effects and is given by injection or nasal spray to treat migraine. The nasal spray formulation is called Migranal and is made by Novartis. You may call the company hotline at 888 697-3543 to obtain a free video on how to use D.H.E. spray. Migranal may be expensive and if you cannot afford the price, a compounding pharmacist can make up generic D.H.E. nasal spray for you at a fraction of the price. Other medications used to treat migraine attacks include capsaicin (0.075% ointment applied in the affected side of your nostrils), Lidocaine nose drops and medications such as Phenergan or Reglan to treat nausea and vomiting. Strong but gentle anti-inflammatory medications include Tolmetin sodium or Diclofenac. Either medication is 10 times stronger than Motrin and very effective. Strong short acting pain medications such as Vicodin ES or Norco 10 may be given. With severe pain, your doctor may prescribe strong short acting pain medications such as Demerol tablets. Long acting strong pain medications such as Oxycontin are not advisable as they may lead to rebound headaches when taken every day or for too long.. Drugs that help control a migraine crisis include an intravenous (IV) infusion of the anti-seizure drug Depacon combined with IV infusion of magnesium sulfate. |
Call your Doctor : If your headache is associated with crossed eyes, paralysis or inability to speak or if it persists for more than 24 hours.
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- Pharmacokinetic–pharmacodynamic correlations and biomarkers in the development of COX-2 inhibitors
- Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats
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- physique et douleur
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Fibromyalgia
Sports Medicine
General Rheumatology
- General
- Arthritis
- Back Pain
- Cancer Pain
- Carpal Tunnel Syndrome
- Diabetes Pain
- HIV/AIDS Pain
- Interstitial Cystitis
- Fibromyalgia Pain
- Labor Pain
- Menstrual Pain
- Migraine Headache
- Reflex Sympathetic Dystrophy
- Sickle Cell Disease
- Shingles/Post-herpetic Neuralgia
- Tension Headache
- Trigeminal Neuralgia
- Vulvodynia
Medical Publications
- The biochemical origin of pain: The origin of all pain is inflammation and the inflammatory response. Part 2 of 3 – Inflammatory profile of pain syndromes
Omoigui S. - The Interleukin-6 inflammation pathway
from cholesterol to aging - Role of statins, bisphosphonates and plant
polyphenols in aging and age-related diseases.
Omoigui S. - The biochemical origin of pain - Proposing a new law of pain: The origin of all pain is inflammation and the inflammatory response. Part 1 of 3 - A unifying law of pain.
Omoigui S. - Bevel Design and not Needle Length determines the Pain Experience in Patients receiving Injections
Omoigui S., Adewumi PA, Do Y, Elenes G. - Cholesterol Synthesis is the Trigger
Omoigui S. MD. - Treatment of ptosis as a complication of botulinum toxin injection
Omoigui S, Irene S. - Subcutaneous Injection of Anakinra
Omoigui S. MD. - A Safer Technique for Epidural Lysis of Adhesions
Omoigui S. MD. - Blind nasal intubation with Audio-Capnometry
Omoigui S, Glass P, Martel DL, Watkins K, Williams KL, Whitefield SM, Wooten LL.
Rheumatology Headlines
Anesthesiology
Pain Management
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BREAKING NEWS!!!!!!:
Page 18 in ARTICLE from Department of Pharmacology, Leiden /Amsterdam Center for Drug Research (LACDR), Faculty of Science, Leiden University STATES:
“we strongly support the hypothesis proposed by OmoiGui, which states that the origin of all pain is inflammation and inflammatory response (5;6).”
Click here to read:
Beyond relief : biomarkers of the anti-inflammatory effect and dose selecion of COX inhibitors in early drug development. Huntjens, Dymphy Regien Hans
Click here to download Full text article from Center for Drug Research:
Click here to read the latest Journal Articles citing Sota Omoigui’s Law of Pain:
BREAKING NEWS!!!!!!:
NOW PUBLISHED – PROCEEDINGS OF THE L.A. PAIN CLINIC
Click here to read the current case report or research article:
Medicinehouse.com Jan 2009; [Epub ahead of print]
Click here to download PDF article:
A critical review of the evidence - Spinal Pain and Fluoroscopic Guided Facet Joint Nerve and Epidural Injection; Full Text Article
BREAKING NEWS!!!!!!:
JUST PUBLISHED - Part 2 of Sota Omoigui’s Law of Pain describing the Inflammatory Profile of Pain Syndromes
Listed on Science Direct Top 25 Hottest Articles
Click here to read:
Med Hypotheses. 2007 Aug 27; [Epub ahead of print]
Click here to download article:
Med Hypotheses. 2007 Aug 27; Full Text Article
NOW AVAILABLE
!!!!!!:
The Biochemical Origin of Pain
Containing Part 1, Part 2 and Unpublished Part 3 of Sota Omoigui’s Law of Pain
Click here to Order Book:
BREAKING NEWS!!!!!!:
JUST PUBLISHED IN THE UK – HOSPITAL DOCTOR profiles Sota Omoigui’s Law of Pain and asks “Is it time for RETHINKING PAIN?”
Click here to read and download:
RETHINKING PAIN
Hospital Doctor 2007 June Pg 24
BREAKING NEWS!!!!!!:
JUST PUBLISHED – Dr Sota Omoigui contributes a chapter in the Textbook – IMMUNE DYSFUNCTION AND IMMUNOTHERAPY IN HEART DISEASE - Edited by: Ronald Ross Watson (Professor of Public Health, School of Medicine, University of Arizona, Tuscon, ) and Douglas Larson.
Click here to view the cover:
Immune Dysfunction and Immunotherapy in Heart Disease
BREAKING NEWS!!!!!!:
In the Journal of Immunity and Ageing, Dr Sota Omoigui describes the Inflammation Pathway from Cholesterol to Aging.
Listed on Immunity and Ageing
Top 10 Most Accessed Articles of All Time
Click here to read:
Immun Ageing. 2007 Mar 20;4(1):1 [Epub ahead of print]
Medical Publications
U.S. Patents
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Our advanced pain therapies have been successful in patients with the most refractory
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ABOUT THE BOOK
Designed for quick access to essential anesthesia drug information, The Handbook is a complete clinical guide in a handy portable format. This pocket reference is packed with tables, descriptions and expanded dosing information covering a broad range of drugs and the various routes of administration commonly used in the practice of anesthesia and critical care. As a synopsis of anesthetic pharmacology it is a useful review for the beginning trainee and the advanced practitioner. An all-time best seller, The Anesthesia Drugs Handbook has been translated into Italian, Japanese, Malaysian, Polish and Portuguese.
Designed for quick access to pain drugs information, Sota Omoigui's Pain Drugs Handbook is a complete clinical guide in a handy portable format. This pocket reference is packed with tables, descriptions and dosages covering a broad range of drugs and the various routes of administration commonly used in the treatment of acute, chronic and cancer pain.
This booklet is written to guide those who suffer or know someone suffering from pain. It provides the most current information about the common painful syndromes, the right medications, useful herbs and various treatments that can be utilized in the home, clinic or hospital to successfully ease pain.
Medications and Plants that prevent and treat Aging, Cardiovascular Disease, Osteoporosis,Arthritis, Type-2 Diabetes, Dementia and Alzheimer’s Disease.
One of the best books on Self Improvement and Management ever published. Animals have been taking care of business much longer than humans and they do it with an instinct few humans possess. Yes, we can learn a lot from the animal kingdom and everyone should read this book. Having been an avid animal behavior student for many years the author has observed their lessons and been awed by them.








